Niels Lorenzen

Niels Lorenzen

Professor

DTU AQUA
National Institute of Aquatic Resources

Public Sector Consultancy

Technical University of Denmark

Kemitorvet

Building 204, room 137

2800 Kgs. Lyngby

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2019
 

Pichia pastoris yeast as a vehicle for oral vaccination of larval and adult teleosts

Embregts, Carmen W.E. ; Reyes-Lopez, Felipe ; Pall, Adina C. ; Stratmann, Ansgar ; Tort, Luis ; Lorenzen, Niels ; Engell-Sorensen, Kirsten ; Wiegertjes, Geert F. ; Forlenza, Maria ; Sunyer, J. Oriol ; Parra, David
in: Fish and Shellfish Immunology, vol: 85, pages: 52-60

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.fsi.2018.07.033

 

A pentavalent vaccine for rainbow trout in Danish aquaculture

Marana, Moonika H ; Sepulveda Araneda, Dagoberto Andres ; Chen, Defang ; Al-Jubury, Azmi ; Jaafar, Rzgar M ; Kania, Per W ; Henriksen, Niels Henrik ; Krossøy, Bjørn ; Dalsgaard, Inger ; Lorenzen, Niels ; Buchmann, Kurt
in: Fish and Shellfish Immunology, vol: 88, pages: 344-351

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.fsi.2019.03.001

 

DNA vaccination for finfish aquaculture

Collins, Catherine ; Lorenzen, Niels ; Collet, Bertrand
in: Fish and Shellfish Immunology, vol: 85, pages: 106-125

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.fsi.2018.07.012

  PDF

Time-course study of the protection induced by an interferon-inducible DNA vaccine against viral haemorrhagic septicaemia in rainbow trout

Sepúlveda, Dagoberto ; Lorenzen, Ellen ; Rasmussen, Jesper Skou ; Einer-Jensen, Katja ; Collet, Bertrand ; Secombes, C. J. ; Lorenzen, Niels
in: Fish and Shellfish Immunology, vol: 85, pages: 99-105

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2019     |    DOI: https://doi.org/10.1016/j.fsi.2018.06.056

2018
 

Virulence marker candidates in N-protein of viral haemorrhagic septicaemia virus (VHSV): virulence variability within VHSV Ib clones

Ito, Takafumi ; Kurita, Jun ; Mori, Koh-ichiro ; Skall, Helle Frank ; Lorenzen, Niels ; Vendramin, Niccolò ; Andersen, Nikolaj Gedsted ; Einer-Jensen, Katja ; Olesen, Niels Jørgen
in: Diseases of Aquatic Organisms, vol: 128, issue: 1, pages: 51-62

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2018     |    DOI: https://doi.org/10.3354/dao03215

2017
  PDF

Intramuscular DNA Vaccination of Juvenile Carp against Spring Viremia of Carp Virus Induces Full Protection and Establishes a Virus-Specific B and T Cell Response

Embregts, Carmen W. E. ; Rigaudeau, Dimitri ; Veselý, Tomas ; Pokorová, Dagmar ; Lorenzen, Niels ; Petit, Jules ; Houel, Armel ; Dauber, Malte ; Schütze, Heike ; Boudinot, Pierre ; Wiegertjes, Geert F. ; Forlenza, Maria
in: Frontiers in Immunology, vol: 8

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2017     |    DOI: https://doi.org/10.3389/fimmu.2017.01340

2015
 

Involvement of two microRNAs in the early immune response to DNA vaccination against a fish rhabdovirus

Bela-ong, Dennis Berbulla ; Schyth, Brian Dall ; Zou, Jun ; Secombes, Christopher J. ; Lorenzen, Niels
in: Vaccine, vol: 33, issue: 28, pages: 3215-3222

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2015     |    DOI: https://doi.org/10.1016/j.vaccine.2015.04.092

2014
 

High virulence differences among phylogenetically distinct isolates of the fish rhabdovirus viral hemorrhagic septicaemia virus are not explained by variability of the surface glycoprotein G or the non-virion protein Nv

Einer-Jensen, Katja ; Harmache, Abdallah ; Biacchesi, Stéphane ; Bremont, Michel ; Stegmann, Anders ; Lorenzen, Niels
in: Journal of General Virology, vol: 95, issue: Pt 2, pages: 307-316

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2014     |    DOI: https://doi.org/10.1099/vir.0.057448-0

2013
 

Inter-species transmission of viral hemorrhagic septicemia virus (VHSV) from turbot (Scophthalmus maximus) to rainbow trout (Onchorhynchus mykiss)

Schönherz, Anna Amanda ; Lorenzen, Niels ; Einer-Jensen, Katja
in: Journal of General Virology, vol: 94, issue: 4, pages: 869-875

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2013     |    DOI: https://doi.org/10.1099/vir.0.048223-0

2012
  PDF

Determining Vaccination Frequency in Farmed Rainbow Trout Using Vibrio anguillarum O1 Specific Serum Antibody Measurements

Holten-Andersen, Lars ; Dalsgaard, Inger ; Nylén, Jørgen ; Lorenzen, Niels ; Buchmann, Kurt
in: P L o S One, vol: 7, issue: 11, pages: e49672

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1371/journal.pone.0049672

 

Efficacy of a glycoprotein DNA vaccine against viral haemorrhagic septicaemia (VHS) in Pacific herring, Clupea pallasii Valenciennes

Hart, L. M. ; Lorenzen, Niels ; LaPatra, S. E. ; Grady, C. A. ; Roon, S. E. ; O’Reilly, J. ; Gregg, J. L. ; Hershberger, P. K.
in: Journal of Fish Diseases Online, vol: 35, issue: 10, pages: 775-779

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1111/j.1365-2761.2012.01364.x

  PDF

In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important

Schyth, Brian Dall ; Bramsen, Jesper Bertram ; Pakula, Malgorzata Maria ; Larashati, Sekar ; Kjems, Jørgen ; Wengel, Jesper ; Lorenzen, Niels
in: Nucleic Acids Research, vol: 40, issue: 10, pages: 4653-4665

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1093/nar/gks033

 

Oral transmission as a route of infection for viral haemorrhagic septicaemia virus in rainbow trout, Oncorhynchus mykiss (Walbaum)

Schönherz, Anna Amanda ; Hansen, M. H. H. ; Jørgensen, H. B. H. ; Berg, P. ; Lorenzen, Niels ; Einer-Jensen, Katja
in: Journal of Fish Diseases Online, vol: 35, issue: 6, pages: 395-406

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1111/j.1365-2761.2012.01358.x

 

Typing of viral hemorrhagic septicemia virus by monoclonal antibodies

Ito, Takafumi ; Kurita, Jun ; Sano, Motohiko ; Skall, Helle Frank ; Lorenzen, Niels ; Einer-Jensen, Katja ; Olesen, Niels Jørgen
in: Journal of General Virology, vol: 93, issue: Pt 12, pages: 2546-2557

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2012     |    DOI: https://doi.org/10.1099/vir.0.043091-0

2011
 

General and family-specific gene expression responses to viral hemorrhagic septicaemia virus infection in rainbow trout (Oncorhynchus mykiss)

Jørgensen, H. B. H. ; Sørensen, P. ; Cooper, G. A. ; Lorenzen, Ellen ; Lorenzen, Niels ; Hansen, M. H. H. ; Koop, B. F. ; Henryon, M.
in: Molecular Immunology, vol: 48, issue: 8, pages: 1046-1058

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1016/j.molimm.2011.01.014

 

Rainbow trout surviving infections of viral haemorrhagic septicemia virus (VHSV) show lasting antibodies to recombinant G protein fragments

Encinas, P. ; Gomez-Casado, E. ; Grandes, Fregeneda ; Olesen, Niels Jørgen ; Lorenzen, Niels ; Estepa, A. ; Coll, J. M.
in: Fish and Shellfish Immunology, vol: 30, issue: 3, pages: 929-935

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2011     |    DOI: https://doi.org/10.1016/j.fsi.2011.01.021

2010
 

Cellular and molecular immune responses of the sea bass (Dicentrarchus labrax) experimentally infected with betanodavirus

Scapigliati, G. ; Buonocore, F. ; Randelli, E. ; Casani, D. ; Meloni, S. ; Zarletti, G. ; Tiberi, M. ; Pietretti, D. ; Boschi, I. ; Manchado, M. ; Martin-Antonio, B. ; Jimenez-Cantizano, R. ; Bovo, G. ; Borghesan, F. ; Lorenzen, Niels ; Einer-Jensen, Katja ; Adams, S. ; Thompson, K. ; Alonso, C. ; Bejar, J. ; Borrego, J.J. ; Alvarez, M.C.
in: Fish and Shellfish Immunology, issue: 28, pages: 303-311

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2010     |    DOI: https://doi.org/10.1016/j.fsi.2009.11.008

 

Immersion exposure of rainbow trout (Oncorhynchus mykiss) fry to wildtype Flavobacterium psychrophilum induces no mortality, but protects against later intraperitoneal challenge

Lorenzen, Ellen ; Brudeseth, B.E. ; Wiklund, T. ; Lorenzen, Niels
in: Fish and Shellfish Immunology, vol: 28, issue: 3, pages: 440-444

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2010     |    DOI: https://doi.org/10.1016/j.fsi.2009.11.025

2009
 

DNA Vaccines against Viral Diseases

Lorenzen, Niels ; Lorenzen, Ellen ; Rasmussen, Jesper Skou ; Einer-Jensen, Katja
in: Gyobyo Kenkyu, vol: 44, issue: 1, pages: 16-18
Presented at:
5th International Symposium of the Japanese-Society-of-Fish-Pathology

Type: Conference article (Peer reviewed)

Status: Published     |    Year: 2009

 

Dual DNA vaccination of rainbow trout (Oncorhynchus mykiss) against two different rhabdoviruses, VHSV and IHNV, induces specific divalent protection

Einer-Jensen, Katja ; Delgado, L. ; Lorenzen, Ellen ; Bovo, G. ; Evensen, Ø. ; LaPatra, S. ; Lorenzen, Niels
in: Vaccine, vol: 27, issue: 8, pages: 1248-1253

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.1016/j.vaccine.2008.12.007

 

Genetic and serological typing of European infectious haematopoietic necrosis virus (IHNV) isolates

Johansson, Tove ; Einer-Jensen, Katja ; Batts, William ; Ahrens, Peter ; Kurath, Gael ; Björklund, Harry ; Lorenzen, Niels
in: Diseases of Aquatic Organisms, vol: 86, issue: 3, pages: 213-221

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.3354/dao02108

 

New tools to study RNA interference to fish viruses: Fish cell lines permanently expressing siRNAs targeting the viral polymerase of viral hemorrhagic septicemia virus

Ruiz, S. ; Schyth, Brian Dall ; Encinas, P. ; Tafalla, Carolina ; Estepa, Amparo ; Lorenzen, Niels ; Coll, Julio
in: Antiviral Research, vol: 82, issue: 3, pages: 148-156

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.1016/j.antiviral.2009.02.200

 

The protective mechanisms induced by a fish rhabdovirus DNA vaccine depend on temperature

Lorenzen, Ellen ; Einer-Jensen, Katja ; Rasmussen, Jesper Skou ; Kjær, Torben Egil ; Collet, B. ; Secombes, C.J. ; Lorenzen, Niels
in: Vaccine, vol: 27, issue: 29, pages: 3870-3880

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2009     |    DOI: https://doi.org/10.1016/j.vaccine.2009.04.012

2008
 

Cell-mediated immune responses in rainbow trout after DNA immunization against the viral hemorrhagic septicemia virus

Utke, Katrin ; Kock, Holger ; Schuetze, Heike ; Bergmann, Sven M. ; Lorenzen, Niels ; Einer-Jensen, Katja ; Köllner, Bernd ; Dalmo, Roy A. ; Vesely, Tomas ; Ototake, Mitsuru ; Fischer, Uwe
in: Developmental & Comparative Immunology, vol: 32, issue: 3, pages: 239-252

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2008     |    DOI: https://doi.org/10.1016/j.dci.2007.05.010

 

Regnbueørredens redning

Vinge, Thomas ; Lorenzen, Niels
in: Dynamo, issue: 12, pages: 28-31

Type: Journal article

Status: Published     |    Year: 2008

2007
 

A High Throughput In Vivo Model for Testing Delivery and Antiviral Effects of siRNAs in Vertebrates

Schyth, Brian Dall ; Lorenzen, Niels ; Pedersen, Finn Skou
in: Molecular Therapy, vol: 15, issue: 7, pages: 1366-72

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2007     |    DOI: https://doi.org/10.1038/sj.mt.6300150

 

Cell-mediated cytotoxicity in rainbow trout, Oncorhynchus mykiss, infected with viral haemorrhagic septicaemia virus

Utke, K. ; Bergmann, S. ; Lorenzen, Niels ; Kollner, B. ; Ototake, M. ; Fischer, U.
in: Fish and Shellfish Immunology, vol: 22, issue: 3, pages: 182-196

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2007     |    DOI: https://doi.org/10.1016/j.fsi.2006.04.008

2006
 

Antiviral activity of Small interfering RNAs: Specificity testing using heterologous virus reveals interferon-related effects overlooked by conventional mismatch controls

Schyth, Brian Dall ; Lorenzen, Niels ; Pedersen, Finn Skou
in: Virology, vol: 349, issue: 1, pages: 134-141

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2006     |    DOI: https://doi.org/10.1016/j.virol.2006.01.009

 

Expression of the glycoprotein of viral haemorrhagic septicaemia virus (VHSV) on the surface of the fish cell line RTG-P1 induces type 1 interferon expression in neighbouring cells

Acosta, F. ; Collet, B. ; Lorenzen, Niels ; Ellis, A.E.
in: Fish & shellfish immunology, vol: 21, issue: 3, pages: 272-278

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2006     |    DOI: https://doi.org/10.1016/j.fsi.2005.12.006

 

Genetic stability of the VHSV consensus sequence of G-gene in diagnostic samples from an acute outbreak

Einer-Jensen, Katja ; Ahrens, Peter ; Lorenzen, Niels
in: Bulletin of The European Association of Fish Pathologists, vol: 26, issue: 2, pages: 62-67

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2006

 

Monitoring of the immune system in fish and shellfish

Lorenzen, Niels ; Evensen, O. ; Cunningham, C. ; Scapigliati, G. ; Alvarez, M.C. ; Roch, P. ; Wiegertjes, G. ; Buchmann, K. ; Adams, A.
in: Bulletin of The European Association of Fish Pathologists, vol: 26, issue: 1, pages: 48-49

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2006

2005
 

DNA vaccines for aquacultured fish

Lorenzen, Niels ; LaPatra, S.E.
in: Revue Scientifique Et Technique-office International Des Epizooties, vol: 24, issue: 1, pages: 201-213

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2005

 

Genotyping of the fish rhabdovirus, viral haemorrhagic septicaemia virus, by restriction fragment length polymorphisms

Einer-Jensen, Katja ; Winton, J. ; Lorenzen, Niels
in: Veterinary Microbiology, vol: 106, issue: 3-4, pages: 167-178

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2005     |    DOI: https://doi.org/10.1016/j.vetmic.2004.12.008

 

Kinetics of Mx expression in rainbow trout (Oncorhynchus mykiss) and Atlantic salmon (Salmo salar L.) parr in response to VHS-DNA vaccination

Acosta, F. ; Petrie, A. ; Lockhart, K. ; Lorenzen, Niels ; Ellis, A.E.
in: Fish & shellfish immunology, vol: 18, issue: 1, pages: 81-89

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2005

 

Parallel phylogenetic analyses using the N, G or Nv gene from a fixed group of VHSV isolates reveal the same overall genetic typing

Einer-Jensen, Katja ; Ahrens, Peter ; Lorenzen, Niels
in: Diseases of Aquatic Organisms, vol: 67, issue: 1-2, pages: 39-45

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2005

 

Time course study of in situ expression of antigens following DNA-vaccination against VHS in rainbow trout (Oncorhynchus mykiss Walbaum) fry

Lorenzen, Ellen ; Lorenzen, Niels ; Einer-Jensen, Katja ; Brudeseth, B. ; Evensen, O.
in: Fish & shellfish immunology, vol: 19, issue: 1, pages: 27-41

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2005     |    DOI: https://doi.org/10.1016/j.fsi.2004.10.009

2004
 

Evolution of the fish rhabdovirus viral haemorrhagic septicaemia virus

Einer-Jensen, Katja ; Ahrens, Peter ; Forsberg, Roald ; Lorenzen, Niels
in: Journal of General Virology, vol: 85, issue: 5, pages: 1167-1179

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2004     |    DOI: https://doi.org/10.1099/vir.0.79820-0

 

Use of plasmid DNA for induction of protective immunity

Lorenzen, Niels
in: Bulletin of The European Association of Fish Pathologists, vol: 24, issue: 1, pages: 11-15

Type: Journal article

Status: Published     |    Year: 2004

2003
 

A DNA vaccine directed against a rainbow trout rhabdovirus induces early protection against a nodavirus challenge in turbot

Sommerset, I. ; Lorenzen, Ellen ; Lorenzen, Niels ; Bleie, H. ; Nerland, A.H.
in: Vaccine, vol: 21, issue: 32, pages: 4661-4667

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2003     |    DOI: https://doi.org/10.1016/S0264-410X(03)00526-7

 

DNA vaccination against viral haemorrhagic septicaemia (VHS) in rainbow trout: size, dose, route of injection and duration of protection-early protection correlates with Mx expression

McLauchlan, P.E. ; Collet, B. ; Ingerslev, Esben ; Secombes, C.J. ; Lorenzen, Niels ; Ellis, A.E.
in: Fish & shellfish immunology, vol: 15, issue: 1, pages: 39-50

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2003     |    DOI: https://doi.org/10.1016/S1050-4648(02)00137-7

2002
 

Immunity induced shortly after DNA vaccination of rainbow trout against rhabdoviruses protects against heterologous virus but not against bacterial pathogens

Lorenzen, Niels ; Lorenzen, Ellen ; Einer-Jensen, Katja ; LaPatra, Scott E.
in: Developmental and Comparative Immunology, vol: 26, issue: 2, pages: 173-179

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2002     |    DOI: https://doi.org/10.1016/S0145-305X(01)00059-3

2001
 

Immunity to viral haemorrhagic septicaemia (VHS) following DNA vaccination of rainbow trout at an early life-stage

Lorenzen, Niels ; Lorenzen, Ellen ; Einer-Jensen, Katja
in: Fish & shellfish immunology, vol: 11, issue: 7, pages: 585-591

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2001     |    DOI: https://doi.org/10.1006/fsim.2001.0337

 

Neutralisation and binding of VHS virus by monovalent antibody fragments

Cupit, P.M. ; Lorenzen, Niels ; Strachan, G. ; Kemp, G.J.L. ; Secombes, C.J. ; Cunningham, C.
in: Virus Research, vol: 81, issue: 1-2, pages: 47-56

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2001     |    DOI: https://doi.org/10.1016/S0168-1702(01)00354-9

 

Protection of rainbow trout against infectious hematopoietic necrosis virus four days after specific or semi-specific DNA vaccination

LaPatra, S.E. ; Corbeil, S. ; Jones, G.R. ; Shewmaker, W.D. ; Lorenzen, Niels ; Anderson, E.D. ; Kurath, G.
in: Vaccine, vol: 19, issue: 28-29, pages: 4011-4019

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2001     |    DOI: https://doi.org/10.1016/S0264-410X(01)00113-X

 

Rainbow trout offspring with different resistance to viral haemorrhagic septicaemia

Slierendrecht, W.J. ; Olesen, Niels Jørgen ; Juul-Madsen, H.R. ; Lorenzen, Niels ; Henryon, M. ; Berg, P. ; Søndergaard, J. ; Koch, C.
in: Fish & shellfish immunology, vol: 11, issue: 2, pages: 155-167

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2001     |    DOI: https://doi.org/10.1006/fsim.2000.0302

2000
 

DNA vaccination of rainbow trout against viral hemorrhagic septicemia virus: A dose-response and time-course study

Lorenzen, Ellen ; Einer-Jensen, Katja ; Martinussen, T. ; LaPatra, S.E. ; Lorenzen, Niels
in: Journal of Aquatic Animal Health, vol: 12, issue: 3, pages: 167-180

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2000

 

Immunoprophylaxis in fish by injection of mouse antibody genes

Lorenzen, Niels ; Cupit, P.M. ; Einer-Jensen, Katja ; Lorenzen, Ellen ; Ahrens, Peter ; Secombes, C.J. ; Cunningham, C.
in: Nature Biotechnology, vol: 18, issue: 11, pages: 1177-1180

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2000     |    DOI: https://doi.org/10.1038/81169

 

Three monoclonal antibodies to the VHS virus glycoprotein: comparison of reactivity in relation to differences in immunoglobulin variable domain gene sequences

Lorenzen, Niels ; Cupit, P.M. ; Secombes, C.J. ; Cunningham, C.
in: Fish & shellfish immunology, vol: 10, issue: 2, pages: 129-142

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 2000     |    DOI: https://doi.org/10.1006/fsim.1999.0232

1999
 

Immunity to rhabdoviruses in rainbow trout: the antibody response

Lorenzen, Niels ; Lapatra, S.E.
in: Fish & shellfish immunology, vol: 9, issue: 4, pages: 345-360

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1999

 

Immunity to VHS virus in rainbow trout

Lorenzen, Niels ; Olesen, Niels Jørgen ; Koch, C.
in: Aquaculture, vol: 172, issue: 1-2, pages: 41-61

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1999     |    DOI: https://doi.org/10.1016/S0044-8486(98)00443-8

 

Isolation of viral haemorrhagic septicaemia virus (VHSV) from wild marine fish species in the Baltic Sea, Kattegat, Skagerrak and the North Sea

Mortensen, Helle Frank ; Heuer, Ole Eske ; Lorenzen, Niels ; Otte, Lars ; Olesen, Niels Jørgen
in: Virus Research, vol: 63, issue: 1-2, pages: 95-106

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1999     |    DOI: https://doi.org/10.1016/S0168-1702(99)00062-3

 

Production of neutralizing antisera against viral hemorrhagic septicemia (VHS) virus by intravenous injections of rabbits

Olesen, Niels Jørgen ; Lorenzen, Niels ; LaPatra, S.E.
in: Journal of Aquatic Animal Health, vol: 11, issue: 1, pages: 10-16

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1999     |    DOI: https://doi.org/10.1577/1548-8667(1999)011<0010:PONAAV>2.0.CO;2

 

Recombinant vaccines: experimental and applied aspects

Lorenzen, Niels
in: Fish & shellfish immunology, vol: 9, issue: 4, pages: 361-365

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1999

1998
 

Characterization of intramolecular disulfide bonds and secondary modifications of the glycoprotein from viral hemorrhagic septicemia virus, a fish rhabdovirus

Einer-Jensen, Katja ; Nielsen, Thomas Krogh ; Roepstorff, Peter ; Lorenzen, Niels
in: Journal of Virology, vol: 72, issue: 12, pages: 10189-10196

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1998

 

Mapping of linear antibody epitopes of the glycoprotein of VHSV, a salmonid rhabdovirus

Fernandez-Alonso, M. ; Lorenzo, G. ; Perez, L. ; Bullido, R. ; Estepa, A. ; Lorenzen, Niels ; Coll, J.M.
in: Diseases of Aquatic Organisms, vol: 34, issue: 3, pages: 167-176

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1998

 

Protective immunity to VHS in rainbow trout (Oncorhynchus mykiss, Walbaum) following DNA vaccination

Lorenzen, Niels ; Lorenzen, Ellen ; Einer-Jensen, Katja ; Heppell, J. ; Wu, T. ; Davis, H.
in: Fish & shellfish immunology, vol: 8, issue: 4, pages: 261-270

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1998

1991
 

Detection of rainbow trout antibody to Egtved virus by enzyme-linked immunosorbent assay (ELISA), immunofluorescence (IF), and plaque neutralization tests (50 %PNT)

Olesen, Niels Jørgen ; Lorenzen, Niels ; Jørgensen, P.E.V.
in: Diseases of Aquatic Organisms, vol: 10, issue: 1, pages: 31-38

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1991

 

Infectious Hematopoietic Necrosis (IHN) and Viral Hemorrhagic Septicemia (VHS): Detection of Trout Antibodies to the Causative Viruses by Means of Plaque Neutralization, Immunofluorescence, and Enzyme-Linked Immunosorbent Assay

Jørgensen, P.E.V. ; Olesen, Niels Jørgen ; Lorenzen, Niels ; Winton, J.R. ; Ristow, S.S.
in: Journal of Aquatic Animal Health, vol: 3, issue: 2, pages: 100–108

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1991

 

Paternal Association of Increased Susceptibility to Viral Haemorrhagic Septicaemia (VHS) in Rainbow Trout (Oncorhynchus mykiss)

Kaastrup, P. ; Hørlyck, Viggo ; Olesen, Niels Jørgen ; Lorenzen, Niels ; Jørgensen, P.E.V. ; Berg, P.
in: Canadian Journal of Fisheries and Aquatic Sciences, vol: 48, issue: 7, pages: 1188–1191

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1991     |    DOI: https://doi.org/10.1139/f91-143

1990
 

Neutralization of Egtved virus pathogenicity to cell cultures and fish by monoclonal antibodies to the viral G protein

Lorenzen, Niels ; Olesen, Niels Jørgen ; Jørgensen, P.E.V.
in: Journal of General Virology, vol: 71, issue: 3, pages: 561-567

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1990     |    DOI: https://doi.org/10.1099/0022-1317-71-3-561

1988
 

Production and Characterization of Monoclonal Antibodies to Four Egtved Virus Structural Proteins

Lorenzen, Niels ; Olesen, Niels Jørgen ; Jørgensen, P.E.V.
in: Diseases of Aquatic Organisms, issue: 4, pages: 35-42

Type: Journal article (Peer reviewed)

Status: Published     |    Year: 1988